Special Symposium of the Harvard Stem Cell Institute: "Breaking the Immune Barrier in Type 1 Diabetes"

Wednesday, October 16, 2013 at 9:00am to 5:00pm

35 Binney Street, Boston, MA

Faculty Organizers: 
Chad Cowan, Arlene Sharpe and Tom Serwold
 
Program:  

9:00 - 9:05 a.m. Intro and welcome - Chad Cowan
 
Session on Clinical Trials/Translational Immunology
Moderator:  Aldo Rossini           
9:05 - 9:35 a.m. Aldo Rossini (Joslin)- "TBA"
9:35 - 10:05 a.m. David Harlan (Univ. MA) -"TBA"
10:05 - 10:35 a.m. Mark Peakman (King's College London) - "The role of the adaptive immune system in beta cell death"   
10:35 - 11:05 a.m. Kevan Herold (Yale) - "TBA"
11:05 - 11:35 a.m. Gordon Weir (Joslin) - "TBA"
11:35 a.m. - 12:35 p.m. LUNCH               
 
Session on tolerance and transplantation   
Moderator:  Arlene Sharpe           
12:40 - 1:00 p.m. Jim Riley (Upenn) - "Engineering Tregs to fight T1D"  
1:00 - 1:20 p.m. Arlene Sharpe (HMS) - "TBA"
1:20 - 1:50 p.m. Dario Vignali (St. Jude's) - "Molecular Control of Treg Stability and Function"  
1:50 - 2:20 p.m. Maria Koulmanda [for Terry Strom] (BIDMC) - "Taming Adverse Inflammation to Prevent and Treat Type 1 Diabetes"
2:20 - 2:50 p.m. Paolo Fiorina (BCH) - "A clinically relevant PD-L1* HSC-based immunotherapy for T1D"
 
2:50 - 3:05 p.m. BREAK 
            
Session on Immunology of Diabetes   
Moderator:  Tom Serwold            
3:10 - 3:40 p.m. Tom Serwold (Joslin) - "Can modifcation of T cell development be used to restore immune tolerance?"
3:40 - 4:00 p.m. Jason Gaglia (Joslin) - "TBA"
4:00 - 4:20 p.m. Stephan Kissler (Joslin) - "Towards a functional understanding of autoimmunity genes"  
4:20 - 4:50 p.m. Ramnik Xavier (MGH) - "Microbes, OMICs and Barrier in T1D"
 
4:50 - 5:00 p.m. Closing remarks, Chad Cowan

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