Tumor Heterogeneity Nanocourse
Tuesday, April 15 at 12:00pm to 3:00pm
Building C, Cannon Room 240 Longwood Avenue
Fransizka Michor, PhD and Kornelia Polyak, MD, PhD: There is a high degree of diversity within tumors despite a largely monoclonal origin, including differences in cellular morphology, cytogenetics, growth rates, cell products, receptors, and immunological characteristics. Together these factors determine neoplastic development, risk of disease progression, and response to therapies. Recent technological developments such as whole-genome sequencing allow us to analyze tumors at unprecedented depths. This nanocourse is designed to provide an introduction and overview of tumor heterogeneity and the current technologies aimed at gleaning multidisciplinary data from tumor populations.
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